Economic endpoints in clinical trials.
نویسنده
چکیده
Economic endpoints are increasingly common in randomized clinical trials. As a relatively new addition to the field, methods of measuring and analyzing cost data are still evolving. These developments will be stimulated by the demands of the public for efficient and effective medical care, which will be based on the findings of clinical trials.
منابع مشابه
Economic evaluations in cancer clinical trials
Authors: Stephen Goodall and Rosalie Viney Prepared: July 2011 SUMMARY • The aim of economic evaluation is to inform clinical and health system decision making and policy • Every time a decision is made about a new technology or treatment, a decision is also made about resource allocation • Economic evaluation is a formal and systematic comparison of the costs and benefits associated with two o...
متن کاملOutcome models in clinical studies: implications for designing and evaluating trials in clinical nutrition.
BACKGROUND & AIMS The selection of appropriate outcome variables in clinical nutrition is particularly challenging, since nutrition is an adjunct therapy in most cases. Therefore, its effect may be confounded with the primary therapy, and classic biomedical outcomes may not reflect the effect of the nutritional intervention. This paper scrutinizes different alternatives to the biomedical perspe...
متن کاملEconomic evaluation of factorial randomised controlled trials: challenges, methods and recommendations
Increasing numbers of economic evaluations are conducted alongside randomised controlled trials. Such studies include factorial trials, which randomise patients to different levels of two or more factors and can therefore evaluate the effect of multiple treatments alone and in combination. Factorial trials can provide increased statistical power or assess interactions between treatments, but ra...
متن کاملChallenges in translating endpoints from trials to observational cohort studies in oncology
Clinical trials are considered the gold standard for examining drug efficacy and for approval of new drugs. Medical databases and population surveillance registries are valuable resources for post-approval observational research, which are increasingly used in studies of benefits and risk of new cancer drugs. Here, we address the challenges in translating endpoints from oncology trials to obser...
متن کاملDo Firms Underinvest in Long-Term Research? Evidence from Cancer Clinical Trials.
We investigate whether private research investments are distorted away from long-term projects. Our theoretical model highlights two potential sources of this distortion: short-termism and the fixed patent term. Our empirical context is cancer research, where clinical trials--and hence, project durations--are shorter for late-stage cancer treatments relative to early-stage treatments or cancer ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Epidemiologic reviews
دوره 24 1 شماره
صفحات -
تاریخ انتشار 2002